Monday, January 19, 2015

Diagnosis: Esophageal Perforation

CT angiogram of the patient's chest revealed extensive pneumomediastinum with mural thickening and mural air within the distal esophagus in addition to adjacent air-fluid levels. Findings suggestive of esophageal perforation including Boerhaave syndrome.

Surgery was urgently consulted and the patient taken to the OR where he underwent primary repair of a distal esophageal perforation and removal of an impacted bezoar with EGD. The patient did well post-operatively and was discharged in stable condition on hospital day 4. 




Esophageal Perforation - Rapid Fire
  • Most common cause of esophageal perforation --> endoscopy 
  • Other causes of esophageal perforation:
    • foreign body ingestion
    • caustic substance ingestion
    • severe esophagitis
    • carcinoma
    • direct injury related to blunt or penetrating trauma
  • Pathophysiology of Boerhaave syndrome --> rapid increase in intraesophageal pressure related to forceful vomiting  
  • More than 90% of spontaneous esophageal ruptures occur in the distal esophagus 
  • Mackler's triad is pathognomonic for spontaneous esophageal rupture
    • subcutaneous emphysema
    • chest pain
    • vomiting
  • Pain associated with distal esophageal rupture often radiates to the back 
  • Hamman's sign or crunch = "crunching" sound auscultated over chest, pathognomonic for mediastinal emphysema 
  • Diagnose with esophagram and/or CT chest
  • Misdiagnosis occurs in half of patients because of the broad differential of chest and abdominal pain
  • Management
    • broad-spectrum antibiotics
    • NPO
    • urgent surgical consult
    • growing body of evidence suggests small, contained iatrogenic perforations can be managed conservatively without surgery
  • Outcome (Kiernan PDThoracic esophageal perforations. Am Surg. 76:1355-1362 2010)
    • 97% survival rate with treatment in first 24 hours
    • 89% with treatment after 24 hours

References: 

Rosen's Emergency Medicine Concepts and Clinical Practice, 8th Ed, 2014, Chapter 89: Esophagus, Stomach, and Duodenum by Jamie M. Hess and Mark J. Lowell

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